Citations:substrate


 * , Jesen A. Fagerness and Dale R. Nyholt, "Basics of DNA and Genotyping", chapter 2 in, 2008, Benjamin M. Neale, et al., editors, Statistical Genetics: Gene mapping through linkage and association, Taylor & Francis, ISBN 9780415410403, page 5:
 * To understand some of the statistical concepts introduced in this book, it is crucial to have some familiarity with the biological and chemical substrates that underlie genetic variation in complex traits. This chapter intends to provide a short overview of the structure and organization of deoxyribose nucleic acid (DNA) for readers who are less familiar with these concepts (Section 2.1). The concepts of recombination and genetic maps are then introduced (Section 2.2). Following this, the stages involved in genotyping are explained at a conceptual level (Section 2.3), as well as an explanation of genotyping technologies (Section 2.4).