a pox on

Etymology
Originally an expression of abuse to wish that someone develop pocks, that is to say, contract pox. Though pox can range from smallpox to chickenpox to cowpox to syphilis, this expression almost always referred to the last one, the Great Pox.

Interjection

 * 1)  To express curses upon (somebody), when irked or wroth, as though wishing someone "a pox".
 * 2)  To hell with (abstract or unalive things).
 * 1)  To hell with (abstract or unalive things).

Synonyms

 * woe betide, fie upon, to hell with