senolysis

Etymology
.

Noun

 * 1)  The destruction of senescent cells, such as to alleviate age-related diseases.
 * 2) * 2020, Joanne Laycock, et al., 7: The Role of Chronic Kidney Disease in Ectopic Calcification, Elena Aikawa, Joshua D. Hutcheson (editors), Cardiovascular Calcification and Bone Mineralization, Springer (Humana Press), page 156,
 * These strategies[to target senescent cells] consist of senolysis, immune-mediated senescent cell clearance and SASP neutralisation.
 * 1) * 2022, Franziska Kellers, et al., Senescence-Associated Molecules and Tumor-Immune-Interactions as Prognostic Biomarkers in Colorectal Cancer, Arndt Hartmann, Luca Di Tommaso (editors), Rising Stars 2021: Pathology, Frontiers in Medicine, page 46,
 * This immune cell-mediated senolysis seems to be facilitated via direct cell-cell contact inducing apoptosis and granule exocytosis.
 * 1) * 2023, Jan O. Nehlin, Chapter 7: Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Ufuk Çakatay, Mehmet Can Atayik (editors), Advances in Protein Chemistry and Structural Biology, Volume 135, Elsevier (Academic Press), page 224,
 * Senolytics are compounds that target selectively senescent cells and induce their lysis, a process known as senolysis. Senescent cells are resistant to apoptosis because they have an increase[d] expression of pro-survival networks.

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