sickness unto death

Etymology
From the book  (1849) by (1813-1855).

Noun

 * 1)  Personal despair over the disquieting circumstances of human existence.
 * 2)  Despair, profound discontent, or a similar persistent debilitating malaise of the mind, spirit, or soul that produces a decline in mental, physical, or societal health and that may culminate in death or dissolution.
 * 1)  Despair, profound discontent, or a similar persistent debilitating malaise of the mind, spirit, or soul that produces a decline in mental, physical, or societal health and that may culminate in death or dissolution.